gene 1,272 words KG: ADORA1
Contents

ADORA1 Gene

🧬 Gene Info
Gene SymbolADORA1
Full NameAdenosine A1 Receptor
Chromosome1q32.1
Functionencodes a 326-amino acid protein that is widely expressed throughout the central and peripheral nervous systems.
Amino Acids326 aa
PathwaysEpigenetic, Synaptic Plasticity
GeneCardsADORA1
Human Protein AtlasADORA1
Associated DiseasesAlzheimer's disease, Epilepsy
Known Drugs/CompoundsCaffeine
InteractionsALZHEIMER, ALZHEIMER'S DISEASE, App, ASTROCYTE, LCN2, MEF2C
KG Connections35 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (4)

CYP46A1 Overexpression Gene Therapy
Score: 0.73
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Excitatory Neuron Vulnerability via SLC17A7 Downregulation
Score: 0.67

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived

See Also (12)

NeuRon Therapeutics
company · KG edge: expressed_in
Neurodegeneration
disease · KG edge: implicated_in
astrocyte-neuron-metabolic-coupling-parkinsons
general · KG edge: activates
Epigenetic Clocks in Neurodegeneration — Causal Drivers
experiment · KG edge: activates
ADORA3 Gene
gene · KG edge: expressed_in

Knowledge Graph (12 edges)

ADORA1 expressed_in ADORA3
ADORA1 associated_with tau pathology
ADORA1 activates TAU
ADORA1 expressed_in MAPT
ADORA1 activates MEF2C
MEF2C activates ADORA1
MAPT expressed_in ADORA1
Caffeine inhibits ADORA1
MAPT upregulates ADORA1
MIR133A downregulates ADORA1

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