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gap 567 words KG: MAPT
Contents

MAPT Mutation Penetrance and Phenotypic Modifiers in Tauopathies

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Wikipedia

Related Hypotheses (2)

Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79Competitive APOE4 Domain Stabilization Peptides
Score: 0.78

Related Analyses (4)

SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completedSleep disruption as cause and consequence of neurodegenerati
neurodegeneration · completedCircuit-level neural dynamics in neurodegeneration
neuroscience · completedTau propagation mechanisms and therapeutic interception poin
neurodegeneration · completed

Related Experiments (21)

Plasma ATN biomarkers across AD continuum in Chilean cohort
clinical · proposed · Score: 0.95Double depletion rescue experiment: tau and MAP6 co-depletio
exploratory · proposed · Score: 0.95Tau depletion effects on neuronal development in primary cul
exploratory · proposed · Score: 0.90Tau depletion effects on neuronal development in primary cul
exploratory · proposed · Score: 0.90Creation and validation of 3xAD-ChAT-Cre mouse model
validation · proposed · Score: 0.90

Knowledge Graph (12 edges)

MAPT encodes TAU
NCSTN interacts_with MAPT
FAS interacts_with MAPT
TNF interacts_with MAPT
LMNA interacts_with MAPT
APH1B interacts_with MAPT
APOE activates MAPT
IL6 interacts_with MAPT
SREBF1 activates MAPT
PSEN2 activates MAPT

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