gene 575 words KG: FZD4
Contents

FZD4 Gene

🧬 Gene Info
Gene SymbolFZD4
Full NameFrizzled Class Receptor 4
Chromosome11q14.2
Protein TypeReceptor
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionendothelial cells, neural progenitors, and mature neurons
Pathwayspathway: - Binds Wnt1, Wnt3, Wnt3A, Wnt5A, Wnt, Wnt Signaling, Wnt signaling, pathway: - Binds Wnt ligands
UniProt IDQ9ULV1
NCBI Gene ID2762
Ensembl IDENSG00000174804
OMIM604579
GeneCardsFZD4
Human Protein AtlasFZD4
Associated DiseasesFamilial Exudative Vitreoretinopathy, Alzheimer's Disease, Stroke
InteractionsPI3K, TGF, WNT
KG Connections9 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Knowledge Graph (9 edges)

FZD4 activates PI3K
FZD4 activates TGF
FZD4 participates_in PI3K-AKT-mTOR signaling
FZD4 participates_in TGF-beta signaling
FZD4 expressed_in microglia
FZD4 activates MICROGLIA
FZD4 activates WNT
FZD4 participates_in blood-brain barrier
FZD4 associated_with WNT

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