gene 749 words KG: ent-gene-9d811bdb
Contents

STXBP1

🧬 Gene Info
Gene SymbolSTXBP1
Full NameMunc18-1
Protein TypeProtein
Functionis a neuronal protein essential for synaptic vesicle release and neurotransmitter secretion.
Primary Expressionnon-neuronal tissues, important for immune function
Molecular Weight66 kDa
Amino Acids594 aa
UniProt IDSearch UniProt
GeneCardsSTXBP1
Human Protein AtlasSTXBP1
Associated DiseasesALS, neurodegeneration
InteractionsDNAJC5, ERK, GENES, HSC70, MUNC18-1, NEURODEGENERATION
KG Connections35 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

Synaptic Vesicle Tau Capture Inhibition
Score: 0.58

Related Analyses (12)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Mitochondrial transfer between neurons and glia
neurodegeneration · completed
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed

Related Experiments (5)

AAV Serotype Comparison for LRRK2 Knockdown in PD Gene Thera
validation · proposed · Score: 0.40
AAV-LRRK2 IND-Enabling Study Design
clinical · proposed · Score: 0.40
Epigenetic Dysregulation Validation in Parkinson's Disease
clinical · proposed · Score: 0.40
AAV-LRRK2 Gene Therapy IND-Enabling Study Design
clinical · proposed · Score: 0.40
Microglial Aging and Immune Memory in Neurodegeneration — Tr
validation · proposed · Score: 0.40

See Also (11)

NeuRon Therapeutics
company · KG edge: expressed_in
Neurodegeneration
disease · KG edge: interacts_with
SCN1A
gene · KG edge: therapeutic_target
Epigenetic Clocks in Neurodegeneration — Causal Drivers
experiment · KG edge: therapeutic_target
Genes
index · KG edge: interacts_with

Knowledge Graph (2 edges)

ent-gene-9d811bdb data_in benchmark_ot_ad_answer_key:STXBP1
benchmark_ot_ad_answer_key:STXBP1 data_in ent-gene-9d811bdb

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