gene 1,578 words KG: ATXN1
Contents

ATXN1 — Ataxin 1

🧬 Gene Info
Gene SymbolATXN1
Full NameAtaxin 1
Chromosome6p22.3.
FunctionCapicua (CIC) repressor complex — Ataxin-1 binds to the transcriptional repressor CIC, regulating downstream target genes
Molecular Weight87 kDa
Amino Acids815 aa
PathwaysNotch signaling
UniProt IDP54253
GeneCardsATXN1
Human Protein AtlasATXN1
Associated DiseasesAtaxia, Huntington's disease, neurodegeneration
InteractionsBDNF, CIC, NEURON, PKA
KG Connections28 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Knowledge Graph (12 edges)

ATXN1 activates BDNF
BDNF inhibits ATXN1
ATXN1 associated_with ATXN2
ATXN1 associated_with NIPA1
ATXN1 associated_with UNC13A
ATXN1 causes neurodegeneration
ATXN1 interacts_with CIC
ATXN1 interacts_with neurodegeneration
ATXN1 causes CIC
ATXN1 causes ATXN2

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