Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SEROTONIN RECEPTOR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | SEROTONIN RECEPTOR |
graph TD
SEROTONIN_RECEPTOR[SEROTONIN RECEPTOR]
SEROTONIN_RECEPTOR -->|binds| serotonin[serotonin]
SEROTONIN_RECEPTOR -->|expressed in| neurons[neurons]
SEROTONIN_RECEPTOR -->|expressed in| hippocampus[hippocampus]
depression[depression] -->|involves| SEROTONIN_RECEPTOR
BDNF[BDNF] -->|activates| SEROTONIN_RECEPTOR
neurodegeneration[neurodegeneration] -->|involves| SEROTONIN_RECEPTOR
GABA[GABA] -->|expressed in| SEROTONIN_RECEPTOR
HTT[HTT] -->|activates| SEROTONIN_RECEPTOR| Target | Relation | Type | Str |
|---|---|---|---|
| serotonin | binds | neurotransmitter | 0.90 |
| neurons | expressed_in | cell_type | 0.80 |
| hippocampus | expressed_in | brain_region | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| depression | involves | disease | 0.70 |
| BDNF | activates | gene | 0.70 |
| GABA | expressed_in | gene | 0.70 |
| neurodegeneration | involves | disease | 0.70 |
| BDNF | expressed_in | gene | 0.70 |
| NLRP3 | activates | gene | 0.60 |
| NLRP3 | expressed_in | gene | 0.60 |
| NLRP3 | causes | gene | 0.60 |
| TNF | associated_with | gene | 0.60 |
| BDNF | causes | gene | 0.60 |
| BDNF | treats | gene | 0.60 |
| NAD | activates | gene | 0.60 |
| NAD | inhibits | gene | 0.60 |
| GABA | treats | gene | 0.60 |
| GABA | activates | gene | 0.60 |
| GABA | causes | gene | 0.60 |
| BDNF | interacts_with | gene | 0.60 |
| BDNF | promotes | gene | 0.60 |
| BDNF | inhibits | gene | 0.60 |
| HTT | activates | gene | 0.60 |
| IFN | associated_with | gene | 0.60 |
| HTT | causes | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning SEROTONIN RECEPTOR in their description or question text
No additional research found