Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RAD51-PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | RAD51 |
| Full Name | PROTEIN |
| Chromosome | 15q15.1 |
| Function | RAD51 is a recombinase protein essential for homologous recombination (HR) repair of double-strand DNA breaks. |
| Primary Expression | all brain regions, with particularly high expression in dopaminergic neurons of the substantia nigra, motor cortex, and hippo |
| Molecular Weight | 37 kDa |
| Amino Acids | 339 aa |
| Pathways | Homologous Recombination |
| UniProt ID | P43251 |
| NCBI Gene ID | 5888 |
| Ensembl ID | ENSG00000102009 |
| OMIM | 179520 |
| GeneCards | RAD51 |
| Human Protein Atlas | RAD51 |
| Associated Diseases | neurodegeneration |
| Interactions | ATM, ATR, BRCA1, CANCER, DNA, FERROPTOSIS |
| KG Connections | 68 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
graph TD
A["Gene expression"] --> B["RAD51 PROTEIN"]
B --> C["Protein folding and
quality control"]
B --> D["Cellular signaling"]
C --> E["Proteostasis"]
D --> F["Neurotoxicity"]
E --> G["Disease outcome"]
F --> G
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
class B protein
class G disease| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning RAD51-PROTEIN in their description or question text
No additional research found