Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about DNAJC30: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | DnaJ Heat Shock Protein Family Member C30 |
| Aliases | DNAJC30 |
| Chromosome | 12p12.1 |
| Function | As a DnaJ-type chaperone, it contains a J-domain that stimulates the ATPase activity of Hsp70 chaperones, facilitating protein folding and preventing aggregation of misfolded proteins[@quiroga2020]. |
| UniProt ID | Q9H0E24 |
| NCBI Gene ID | 54538 |
| OMIM | 617094 |
| Associated Diseases | Glioblastoma, Ms |
| KG Connections | 7 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
DNAJC30["DNAJC30"]
Ms{"Ms"}
DNAJC30 -->|"associated with"| Ms
Glioblastoma{"Glioblastoma"}
DNAJC30 -->|"associated with"| Glioblastoma
GBM["GBM"]
DNAJC30 -->|"associated with"| GBM
CTSD["CTSD"]
DNAJC30 -->|"associated with"| CTSD
neurodegeneration["neurodegeneration"]
DNAJC30 -->|"implicated in"| neurodegeneration
PTPRN2["PTPRN2"]
PTPRN2 -->|"associated with"| DNAJC30
style DNAJC30 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| Ms | associated_with | disease | 0.65 |
| Glioblastoma | associated_with | disease | 0.65 |
| GBM | associated_with | gene | 0.60 |
| CTSD | associated_with | gene | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| genes-dnajc30 | linked_to | wiki | 1.00 |
| genes-dnajc30 | describes | wiki | 0.90 |
| PTPRN2 | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning DNAJC30 in their description or question text
No additional research found