gene 639 words KG: DNAJC30
Contents

DNAJC30 Gene

🧬 Gene Info
Gene SymbolDnaJ Heat Shock Protein Family Member C30
AliasesDNAJC30
Chromosome12p12.1
FunctionAs a DnaJ-type chaperone, it contains a J-domain that stimulates the ATPase activity of Hsp70 chaperones, facilitating protein folding and preventing aggregation of misfolded proteins[@quiroga2020].
UniProt IDQ9H0E24
NCBI Gene ID54538
OMIM617094
Associated DiseasesGlioblastoma, Ms
KG Connections6 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (3)

SASP-Mediated Complement Cascade Amplification
Score: 0.91
CYP46A1 Overexpression Gene Therapy
Score: 0.92
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (4)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (7)

Proposed experiment from debate on Synaptic pruning by micro
falsification · proposed · Score: 0.40
Proposed experiment from debate on Senolytics targeting p16/
falsification · proposed · Score: 0.40
Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?
clinical · proposed · Score: 0.40
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40
Mixed Pathology Effects on Parkinson's Disease Progression a
clinical · proposed · Score: 0.40

See Also (4)

Neurodegeneration
disease · KG edge: implicated_in
CTSD — Cathepsin D
gene · KG edge: associated_with
GLI Gene Family
gene · KG edge: associated_with
PTPRN2 — Protein Tyrosine Phosphatase Receptor Type N2
gene · KG edge: associated_with

Knowledge Graph (6 edges)

PTPRN2 associated_with DNAJC30
DNAJC30 associated_with GBM
DNAJC30 associated_with CTSD
genes-dnajc30 linked_to DNAJC30
DNAJC30 associated_with Ms
DNAJC30 associated_with Glioblastoma

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