Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ADIPOGENESIS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | ADIPOGENESIS |
graph TD
ADIPOGENESIS[ADIPOGENESIS]
m6A[m6A] -->|regulates| ADIPOGENESIS
PIEZO1[PIEZO1] -->|activates| ADIPOGENESIS
TREK_1_Inhibition[TREK-1 Inhibition] -->|activates| ADIPOGENESIS
Kcnk2_Downregulation[Kcnk2 Downregulation] -->|promotes| ADIPOGENESIS
Ceramide_Accumulation[Ceramide Accumulation] -->|suppresses| ADIPOGENESIS
ceramide[ceramide] -->|suppresses| ADIPOGENESIS
FTO[FTO] -->|activates| ADIPOGENESIS
FOXO[FOXO] -->|inhibits| ADIPOGENESIS
PAQR4[PAQR4] -->|suppresses| ADIPOGENESIS| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| m6A | regulates | protein | 0.90 |
| ceramide | suppresses | compound | 0.90 |
| PAQR4 | suppresses | gene | 0.90 |
| TREK-1 Inhibition | activates | mechanism | 0.90 |
| Kcnk2 Downregulation | promotes | mechanism | 0.90 |
| 38961186 | suppresses | paper | 0.90 |
| PIEZO1 | activates | protein | 0.90 |
| FTO | activates | protein | 0.90 |
| FTO | regulates | protein | 0.90 |
| FOXO | inhibits | protein | 0.90 |
| Ceramide Accumulation | suppresses | process | 0.90 |
| Membrane Potential Increase | promotes | mechanism | 0.88 |
| FGFR1 | activates | protein | 0.80 |
| autophagy | associated_with | pathway | 0.80 |
| KCNK2 | regulates | gene | 0.80 |
| Mitochondrial Dysfunction-Associated Senescence | suppresses | phenotype | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning ADIPOGENESIS in their description or question text
No additional research found