Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about VASCULAR REMODELLING: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | VASCULAR REMODELLING |
graph TD
VASCULAR_REMODELLING["VASCULAR REMODELLING"]
Inflammation["Inflammation"] -->|"contributes to"| VASCULAR_REMODELLING
VEGF["VEGF"] -->|"involved_in"| VASCULAR_REMODELLING
PDGF["PDGF"] -->|"involved_in"| VASCULAR_REMODELLING
Reactive_Oxygen_Species["Reactive Oxygen Species"] -->|"involved_in"| VASCULAR_REMODELLING
TGFB1["TGFB1"] -->|"involved_in"| VASCULAR_REMODELLING
Rho_ROCK_Pathway["Rho/ROCK Pathway"] -->|"involved_in"| VASCULAR_REMODELLING
MAPK_Pathway["MAPK Pathway"] -->|"involved_in"| VASCULAR_REMODELLING
MicroRNAs["MicroRNAs"] -->|"regulates"| VASCULAR_REMODELLING| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| Hypertension | associated_with | disease | 0.95 |
| Atherosclerosis | associated_with | disease | 0.95 |
| Inflammation | contributes_to | process | 0.92 |
| VEGF | involved_in | protein | 0.90 |
| TGFB1 | involved_in | protein | 0.90 |
| PDGF | involved_in | protein | 0.90 |
| Heart Failure | associated_with | disease | 0.90 |
| Rho/ROCK Pathway | involved_in | pathway | 0.88 |
| MAPK Pathway | involved_in | pathway | 0.88 |
| Long Noncoding RNAs | regulates | biomarker | 0.88 |
| MicroRNAs | regulates | biomarker | 0.88 |
| Nitric Oxide | modulates | compound | 0.85 |
| IL1B | contributes_to | protein | 0.85 |
| TNF | contributes_to | protein | 0.85 |
| Superoxide | modulates | compound | 0.85 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning VASCULAR REMODELLING in their description or question text
No additional research found