gene

TNR

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TNR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

12Connections

0Hypotheses

0Analyses

7Outgoing

5Incoming

0Experiments

0Debates

Summary

TNR Gene — Tenascin R

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🧬 Gene Info

Gene Symbol	TNR
Full Name	Tenascin R
Chromosome	1q32.1
Function	is an extracellular matrix glycoprotein expressed primarily in the central nervous system.
Primary Expression	the central nervous system
Molecular Weight	160 kDa
Amino Acids	400 aa
Exons	26
Ensembl ID	ENSG00000132640
GeneCards	TNR
Human Protein Atlas	TNR
Associated Diseases	neurodegeneration
KG Connections	12 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (3)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    TNR["TNR"]
    TNR -->|"expressed in"| HUNTINGTIN["HUNTINGTIN"]
    TNR -->|"contributes to"| NEURODEGENERATIVE_DISORDERS["NEURODEGENERATIVE DISORDERS"]
    TNR -->|"expressed in"| Huntingtin["Huntingtin"]
    TNR -->|"expressed in"| Spinal_Cord["Spinal Cord"]
    TNR -->|"implicated in"| neurodegeneration["neurodegeneration"]
    GENES["GENES"] -->|"causes"| TNR
    DNA["DNA"] -->|"encodes"| TNR
    HUNTINGTIN -->|"expressed in"| TNR

Outgoing (7)

Target	Relation	Type	Str
NEURODEGENERATIVE DISORDERS	contributes_to	gene	0.60
Huntingtin	expressed_in	protein	0.60
HUNTINGTIN	expressed_in	gene	0.60
DNA	associated_with	gene	0.60
Ras	associated_with	protein	0.60
App	associated_with	protein	0.60
Spinal Cord	expressed_in	brain_region	0.55

Incoming (5)

Source	Relation	Type	Str
GENES	causes	gene	0.60
DNA	associated_with	gene	0.60
REPEAT-CONTAINING TRANSCRIPTS	associated_with	gene	0.60
DNA	encodes	gene	0.60
HUNTINGTIN	expressed_in	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning TNR in their description or question text

No additional research found

TNR