concept

SURVIVIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SURVIVIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

36Connections

0Hypotheses

0Analyses

20Outgoing

16Incoming

0Experiments

0Debates

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💡 Concept Info

Name	SURVIVIN
Key Genes/Proteins	Actin, AND, AURKA, CANCER, DNA, FBXL7
Related Diseases	Aging, Cancer
Related Pathways	Cell Cycle, Proteasome, Ubiquitin-Proteasome

Pathway Diagram

graph TD
    SURVIVIN["SURVIVIN"]
    SURVIVIN -->|"binds"| FBXL7["FBXL7"]
    SURVIVIN -->|"promotes"| Drug_Resistance["Drug Resistance"]
    SURVIVIN -.biomarker for.-> Gastric_Cancer_Prognosis["Gastric Cancer Prognosis"]
    SURVIVIN -->|"inhibits"| Apoptosis["Apoptosis"]
    SURVIVIN -->|"activates"| Cancer["Cancer"]
    SURVIVIN -->|"activates"| Aging["Aging"]
    SURVIVIN -->|"activates"| AND["AND"]
    AURKA["AURKA"] -->|"upregulates"| SURVIVIN
    FBXL7 -->|"degrades"| SURVIVIN
    GABPB1["GABPB1"] -->|"regulates"| SURVIVIN
    DNA["DNA"] -->|"activates"| SURVIVIN

Outgoing (20)

Target	Relation	Type	Str
FBXL7	binds	protein	0.90
Drug Resistance	promotes	phenotype	0.90
Drug Resistance	mediates	phenotype	0.90
Apoptosis	inhibits	process	0.87
Gastric Cancer Prognosis	biomarker_for	biomarker	0.87
Cancer	therapeutic_target	disease	0.65
Cancer	activates	disease	0.65
Aging	activates	disease	0.65
CANCER	activates	gene	0.60
Proteasome	activates	pathway	0.60
FBXL7	regulates	gene	0.60
Ubiquitin-Proteasome	activates	pathway	0.60
Cell Cycle	activates	pathway	0.60
AND	activates	gene	0.60
FOXP1	regulates	gene	0.60
Ubiquitin-Proteasome	degrades	pathway	0.60
Actin	activates	protein	0.60
Rb	activates	protein	0.60
UBIQUITIN	activates	gene	0.35
UBIQUITIN-PROTEASOME	activates	process	0.35

Incoming (16)

Source	Relation	Type	Str
FBXL7	binds	protein	0.95
AURKA	upregulates	gene	0.95
UBIQUITIN	targets	protein	0.95
FBXL7	targets	protein	0.92
AURKA	regulates	gene	0.90
AURKA	correlates_with	gene	0.85
GABPB1	regulates	gene	0.80
AURKA	regulates_stability_by_targeting_FBXL7	gene	0.80
FOXP1	regulates	gene	0.60
UBIQUITIN	degrades	gene	0.60
AURKA	activates	gene	0.60
DNA	activates	gene	0.60
FBXL7	regulates	gene	0.60
UBIQUITIN	activates	gene	0.60
CANCER	regulates	disease	0.35
CANCER	activates	disease	0.35

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SURVIVIN in their description or question text

No additional research found