concept

OLFML3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about OLFML3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

31Connections
0Hypotheses
0Analyses
16Outgoing
15Incoming
0Experiments
0Debates

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💡 Concept Info
NameOLFML3
Key Genes/ProteinsCLOCK, GBM, LOX, Nf-Κb, PATZ1, PD1
Related Diseasesglioblastoma
Related PathwaysNF-kB signaling, NF-κB-PATZ1

Pathway Diagram

graph TD
    OLFML3[OLFML3]
    OLFML3 -->|expressed in| Microglia[Microglia]
    OLFML3 -->|regulates| Microglia_Infiltration[Microglia Infiltration]
    OLFML3 -->|activates| microglia_infiltration[microglia infiltration]
    OLFML3 -->|expressed in| microglia[microglia]
    OLFML3 -->|activates| PTEN[PTEN]
    OLFML3 -->|inhibits| PD1[PD1]
    OLFML3 -->|activates| PATZ1[PATZ1]
    OLFML3 -->|expressed in| macrophages[macrophages]
    NF__B_PATZ1[NF-κB-PATZ1] -->|upregulates| OLFML3
    PATZ1 -->|regulates| OLFML3
    Nf__b[Nf-Κb] -->|upregulates| OLFML3
    LOX[LOX] -->|regulates| OLFML3
    CLOCK[CLOCK] -->|regulates| OLFML3
    GBM[GBM] -->|activates| OLFML3

Outgoing (16)

TargetRelationTypeStr
benchmark_ot_ad_answer_key:OLFML3data_indataset_row0.00
Microgliaexpressed_incell_type0.95
Microglia Infiltrationregulatesprocess0.90
Microglia Infiltrationmediatesprocess0.85
microglia infiltrationactivatesprocess0.70

Incoming (15)

SourceRelationTypeStr
benchmark_ot_ad_answer_key:OLFML3data_indataset_row0.00
NF-κB-PATZ1upregulatespathway0.90
Nf-Κbupregulatesprotein0.85
PATZ1regulatesgene0.85
NF-κB-PATZ1activatespathway0.70

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning OLFML3 in their description or question text

No additional research found