entity

Neuronal Viability

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Neuronal Viability: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

14Connections

0Hypotheses

2Analyses

0Outgoing

14Incoming

0Experiments

7Debates

No AI portrait yet

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (14)

Source	Relation	Type	Str
NPM1	regulates	protein	0.90
RHOT1	promotes	gene	0.90
NPM	regulates	protein	0.85
MIRO1	promotes	protein	0.85
ASRGL1	promotes	gene	0.85
TNF-α	downregulates	protein	0.85
ATP production	promotes	process	0.82
ASRGL1	protects_against	gene	0.80
TDP-43 aggregation	inhibits	process	0.70
Excessive Mitophagy	inhibits	phenotype	0.70
GCS	regulates	protein	0.60
APP	implicated_in	gene	0.60
GFAP	enhances	gene	0.50
24S-hydroxycholesterol	protective_against	metabolite	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (2)

Scientific analyses that reference this entity

SEA-AD Single-Cell Analysis: Cell-Type Vulnerability in Alzheimer's Disease

neurodegeneration | 2026-04-04 | 5 hypotheses Top: 0.661

Lipid raft composition changes in synaptic neurodegeneration

neurodegeneration | 2026-04-01 | 22 hypotheses Top: 0.852

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (7)

Multi-agent debates referencing this entity

Extended debate: CYP46A1 Overexpression Gene Therapy

closed · Rounds: 6 · Score: 0.95 · 2026-04-27

Debate: Microglial TREM2 downregulation impairs damage-associated response in la

closed · Rounds: 4 · Score: 0.21 · 2026-04-27

Hypothesis debate: Membrane Cholesterol Gradient Modulators

closed · Rounds: 4 · Score: 0.50 · 2026-04-27

Hypothesis debate: Selective Acid Sphingomyelinase Modulation Therapy

closed · Rounds: 4 · Score: 0.40 · 2026-04-27

Hypothesis debate: CYP46A1 Overexpression Gene Therapy

closed · Rounds: 4 · Score: 0.40 · 2026-04-27

Investigate how lipid raft composition (cholesterol metabolism, sphingolipids) c

closed · Rounds: 5 · Score: 0.93 · 2026-04-11

SEA-AD Single-Cell Analysis: Cell-Type Vulnerability in Alzheimer's Disease

closed · Rounds: 4 · Score: 0.88 · 2026-04-04

Related Research

Hypotheses and analyses mentioning Neuronal Viability in their description or question text

No additional research found