protein

NRSF

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NRSF: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

10Connections

0Hypotheses

0Analyses

8Outgoing

2Incoming

0Experiments

0Debates

Summary

Page for NRSF Protein

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🔬 Protein Info

Gene Symbol	NRSF
Function	In the mature nervous system, NRSF continues to play important roles in synaptic plasticity, neuronal homeostasis, and stress responses. Its dysregulation contributes to transcriptional changes tha...
Molecular Weight	200 kDa
Amino Acids	094 aa
Pathways	epigenetic regulation
GeneCards	NRSF
Human Protein Atlas	NRSF
Interactions	DLG4, GRIA1, PSD-95, REST, SYN1, SYP
KG Connections	10 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

NRSF Protein

protein · 1429 words

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Pathway Diagram

graph TD
    NRSF(["NRSF"])
    style NRSF fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff
    neurons["neurons"]
    PSD_95(["PSD-95"])
    REST["REST"]
    SYN1["SYN1"]
    SYP["SYP"]
    epigenetic_regulation["epigenetic regulation"]
    DLG4["DLG4"]
    GRIA1["GRIA1"]

    NRSF -->|"expressed_in"| neurons
    NRSF -.->|"inhibits"| PSD_95
    NRSF -.->|"inhibits"| REST
    NRSF -.->|"inhibits"| SYN1
    NRSF -.->|"inhibits"| SYP
    NRSF -->|"participates_in"| epigenetic_regulation
    NRSF -->|"regulates"| REST
    DLG4 -.->|"inhibits"| NRSF
    GRIA1 -.->|"inhibits"| NRSF

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef drug fill:#1a2a2a,stroke:#80cbc4,color:#e0e0e0
    class neurons mechanism
    class PSD_95 protein
    class REST gene
    class SYN1 gene
    class SYP gene
    class epigenetic_regulation protein
    class DLG4 gene
    class GRIA1 gene

Outgoing (8)

Target	Relation	Type	Str
neurons	expressed_in	cell_type	0.65
REST	activates	gene	0.60
REST	regulates	gene	0.55
PSD-95	inhibits	gene	0.55
REST	inhibits	gene	0.55
SYN1	inhibits	gene	0.55
SYP	inhibits	gene	0.55
epigenetic regulation	participates_in	pathway	0.55

Incoming (2)

Source	Relation	Type	Str
DLG4	inhibits	gene	0.55
GRIA1	inhibits	gene	0.55

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning NRSF in their description or question text

No additional research found