Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NK CELLS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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graph TD
NK_CELLS[NK CELLS]
NK_CELLS -->|produces| CYTOKINES[CYTOKINES]
NK_CELLS -->|implicated in| ROS[ROS]
NK_CELLS -->|inhibits| PHAGOCYTOSIS[PHAGOCYTOSIS]
unfolded_protein_response[unfolded protein response] -->|active_in| NK_CELLS
CD33[CD33] -->|targets| NK_CELLS
dopamine_receptor[dopamine receptor] -->|expressed in| NK_CELLS
stroke[stroke] -->|affects| NK_CELLS
AQP4[AQP4] -->|accumulates_in| NK_CELLS
IFN[IFN] -->|implicated in| NK_CELLS
CYTOKINES -->|implicated in| NK_CELLS
ENDOTHELIAL_CELLS[ENDOTHELIAL CELLS] -->|implicated in| NK_CELLS
DENDRITIC_CELLS[DENDRITIC CELLS] -->|implicated in| NK_CELLS
MACROPHAGES[MACROPHAGES] -->|implicated in| NK_CELLS| Target | Relation | Type | Str |
|---|---|---|---|
| ionizing radiation | associated_with | compound | 0.70 |
| CYTOKINES | produces | phenotype | 0.65 |
| STROKE | co_discussed | disease | 0.40 |
| ROS | implicated_in | protein | 0.35 |
| PHAGOCYTOSIS | inhibits | process | 0.35 |
| STROKE | associated_with | disease | 0.35 |
| Source | Relation | Type | Str |
|---|---|---|---|
| GZMB | associated_with | gene | 0.80 |
| unfolded protein response | active_in | pathway | 0.70 |
| CD33 | targets | gene | 0.65 |
| IFN | implicated_in | gene | 0.60 |
| dopamine receptor | expressed_in | receptor | 0.60 |
| stroke | affects | disease | 0.60 |
| AQP4 | accumulates_in | gene | 0.60 |
| CYTOKINES | implicated_in | protein | 0.50 |
| INFLAMMATION | co_discussed | process | 0.40 |
| MICROGLIA | inhibits | cell_type | 0.35 |
| INFLAMMATION | associated_with | process | 0.35 |
| ENDOTHELIAL CELLS | implicated_in | cell_type | 0.35 |
| MONOCYTES | implicated_in | cell_type | 0.35 |
| HEPATOCYTES | implicated_in | cell_type | 0.35 |
| DENDRITIC CELLS | implicated_in | cell_type | 0.35 |
| MACROPHAGES | implicated_in | cell_type | 0.35 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning NK CELLS in their description or question text
No additional research found