protein

NGFRPROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NGFRPROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Debates

Summary

NGFR (nerve growth factor receptor), also known as p75NTR or CD271, is a member of the tumor necrosis factor receptor superfamily.

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🔬 Protein Info

Gene Symbol	NGFRPROTEIN
Chromosome	17q21.33
Protein Type	Receptor
Function	is a member of the tumor necrosis factor receptor superfamily.
Subcellular Localization	** Cell surface, lipid rafts, endosomes, nucleus ## Normal Function p75NTR is
Molecular Weight	75 kDa
GeneCards	NGFRPROTEIN
Human Protein Atlas	NGFRPROTEIN
Associated Diseases	Alzheimer, Neuropathy
Interactions	ABCA7, ALZHEIMER, ALZHEIMER'S DISEASE, BDNF, CDH1, CTNNB1
KG Connections	39 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

NGFR (p75NTR) Protein

protein · 609 words

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Pathway Diagram

graph TD
    NGFRPROTEIN["NGFRPROTEIN"]
    neurodegeneration["neurodegeneration"]
    NGFRPROTEIN -->|"implicated_in"| neurodegeneration
    style NGFRPROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning NGFRPROTEIN in their description or question text

No additional research found