Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NEUROLOGICAL DISORDERS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | NEUROLOGICAL DISORDERS |
graph TD
NEUROLOGICAL_DISORDERS["NEUROLOGICAL DISORDERS"]
MIRO1["MIRO1"] -->|"targets"| NEUROLOGICAL_DISORDERS
DNA_Methylation["DNA Methylation"] -->|"involved_in"| NEUROLOGICAL_DISORDERS
Neurorehabilitation["Neurorehabilitation"] -->|"treats"| NEUROLOGICAL_DISORDERS
Antisense_Oligonucleotides["Antisense Oligonucleotides"] -->|"treats"| NEUROLOGICAL_DISORDERS
DNA_Methylation_Inhibitors["DNA Methylation Inhibitors"] -->|"treats"| NEUROLOGICAL_DISORDERS
Aging["Aging"] -->|"risk_factor_for"| NEUROLOGICAL_DISORDERS
Blood_Brain_Barrier_Impairment["Blood-Brain Barrier Impairment"] -->|"contributes to"| NEUROLOGICAL_DISORDERS
Molecular_Imaging_Agents["Molecular Imaging Agents"] -.biomarker for.-> NEUROLOGICAL_DISORDERS| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| ANNEXINS | involved_in | protein | 1.00 |
| MIRO1 | targets | gene | 0.95 |
| DNA Methylation | involved_in | process | 0.95 |
| Epigenetic Changes | associated_with | mechanism | 0.90 |
| Neuroinflammation | contributes_to | process | 0.90 |
| Gut Microbiome | associated_with | process | 0.90 |
| Miro1 | associated_with | protein | 0.90 |
| Neurorehabilitation | treats | process | 0.90 |
| MIRO1 | associated_with | protein | 0.90 |
| Blood-Cns Barrier Disruption | associated_with | process | 0.88 |
| MTOR | associated_with | gene | 0.85 |
| MALAT1 | associated_with | gene | 0.85 |
| Aging | risk_factor_for | process | 0.85 |
| Evidence-Based Treatment Procedures | treats | process | 0.85 |
| ALOX15 | implicated_in | gene | 0.85 |
| Evidence-Based Treatment Procedures | involved_in | process | 0.85 |
| Molecular Imaging Agents | biomarker_for | compound | 0.85 |
| Antisense Oligonucleotides | treats | drug | 0.85 |
| DNA Methylation Inhibitors | treats | drug | 0.85 |
| VCP | implicated_in | gene | 0.85 |
| Blood-Brain Barrier Impairment | contributes_to | phenotype | 0.85 |
| Induced Pluripotent Stem Cells | treats | cell_type | 0.82 |
| Neural Stem Cells | treats | cell_type | 0.82 |
| Mesenchymal Stem Cells | treats | cell_type | 0.82 |
| Blood-Cns Barrier Hyperpermeability | contributes_to | phenotype | 0.82 |
| MIRO1 | is_potential_target_for_treating | gene | 0.80 |
| ZFPs | implicated_in | protein | 0.80 |
| CCL2/CCR2 pathway | contributes_to | pathway | 0.80 |
| MIRO1 | is_a_potential_target_for_treating | protein | 0.80 |
| Mitochondrial Dysfunction | contributes_to | process | 0.80 |
| PROANTHOCYANIDINS | protects_against | compound | 0.80 |
| MIRO1 | biomarker_for | gene | 0.80 |
| glymphatic pathway | implicated_in | process | 0.80 |
| Glymphatic Pathway | involved_in | pathway | 0.80 |
| Phytochemicals | protects_against | compound | 0.80 |
| DNA METHYLATION | associated_with | biological_process | 0.80 |
| HISTONE MODULATION | associated_with | biological_process | 0.80 |
| Senescence | associated_with | biological_process | 0.80 |
| CGAS | associated_with | gene | 0.80 |
| Noncoding RNAs | associated_with | biomarker | 0.80 |
| Personalized Ipsc-Derived Therapies | treats | process | 0.78 |
| Embryonic Stem Cells | treats | cell_type | 0.78 |
| cGAS Inhibitors | treats | drug | 0.75 |
| autophagy dysfunction | causes | process | 0.70 |
| ANNEXINS | implicated in | protein | 0.70 |
| ANNEXINS | implicated_in | protein | 0.70 |
| 39036341 | has potential in preventing and treating | paper | 0.60 |
| SLC6A13 | implicated_in | gene | 0.60 |
| SPP1 | implicated_in | gene | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning NEUROLOGICAL DISORDERS in their description or question text
No additional research found