Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ANNEXINS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | ANNEXINS |
| Related Diseases | Alzheimer's Disease, CNS tumors, neurological disorders |
graph TD
ANNEXINS["ANNEXINS"]
ANNEXINS -->|"involved_in"| Central_Nervous_System_Develop["Central Nervous System Development"]
ANNEXINS -->|"involved_in"| Calcium_Signaling["Calcium Signaling"]
ANNEXINS -->|"involved_in"| Membrane_Organization["Membrane Organization"]
ANNEXINS -->|"involved_in"| Neuronal_Development["Neuronal Development"]
ANNEXINS -->|"modulates"| Neuronal_Differentiation["Neuronal Differentiation"]
ANNEXINS -->|"modulates"| CNS_Tumor_Growth["CNS Tumor Growth"]
ANNEXINS -->|"involved_in"| CNS_Development["CNS Development"]| Target | Relation | Type | Str |
|---|---|---|---|
| central nervous system functioning | involved_in | process | 1.00 |
| CNS tumors | involved_in | disease | 1.00 |
| neurological disorders | involved_in | disease | 1.00 |
| Central Nervous System Development | involved_in | process | 0.95 |
| Calcium Signaling | involved_in | process | 0.90 |
| Membrane Organization | involved_in | process | 0.90 |
| Phospholipid Binding | mediates | mechanism | 0.90 |
| Neuronal Development | involved_in | process | 0.90 |
| Cns Tumors | contributes_to | disease | 0.85 |
| Tumor Angiogenesis | modulates | process | 0.85 |
| Exocytosis | involved_in | process | 0.85 |
| Endocytosis | involved_in | process | 0.85 |
| Neuroinflammation | modulates | process | 0.85 |
| CNS Tumor Growth | modulates | phenotype | 0.85 |
| CNS Development | involved_in | process | 0.85 |
| Neuronal Differentiation | modulates | process | 0.85 |
| Neuronal Development | associated_with | process | 0.85 |
| Cell Signaling | modulates | process | 0.85 |
| Synaptic Formation | involved_in | process | 0.85 |
| Alzheimer's Disease | associated_with | disease | 0.85 |
| CNS Tumor Growth | contributes_to | phenotype | 0.80 |
| Multiple Sclerosis | associated_with | disease | 0.80 |
| Neuroinflammation | contributes_to | process | 0.80 |
| Exocytosis | involved_in | process | 0.80 |
| Apoptosis | modulates | process | 0.80 |
| Synaptic Formation | modulates | process | 0.80 |
| Neuronal Differentiation | associated_with | process | 0.80 |
| central nervous system development | regulates | process | 0.80 |
| Endocytosis | involved_in | process | 0.80 |
| Depression | associated_with | disease | 0.80 |
| Alzheimer'S Disease | associated_with | disease | 0.80 |
| Alzheimer's Disease | involved_in | disease | 0.75 |
| neuroinflammation | regulates | process | 0.75 |
| neuronal differentiation | regulates | process | 0.75 |
| Tumor Invasion | modulates | process | 0.75 |
| Angiogenesis | involved_in | process | 0.75 |
| tumor invasion | contributes_to | process | 0.70 |
| central nervous system development | play role in | process | 0.70 |
| central nervous system functioning | play role in | process | 0.70 |
| neurological disorders | implicated in | disease | 0.70 |
| CNS tumors | implicated in | disease | 0.70 |
| neurological disorders | implicated_in | disease | 0.70 |
| synaptic formation | associated_with | process | 0.70 |
| CNS tumor growth | promotes | phenotype | 0.70 |
| angiogenesis | modulates | process | 0.65 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning ANNEXINS in their description or question text
No additional research found