gene

SLC6A13

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SLC6A13: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

5Connections

0Hypotheses

0Analyses

5Outgoing

0Incoming

0Experiments

0Debates

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🧬 Gene Info

Gene Symbol	SLC6A13
Full Name	Solute Carrier Family 6 Member 13 (GABA Transporter 2, GAT2)
Chromosome	12p13.33
Function	encodes a membrane transport protein responsible for the uptake of gamma-aminobutyric acid (GABA) from the extracellular space.
Primary Expression	astrocytes but at lower levels than GAT3 (SLC6A11) [5]:
Molecular Weight	63 kDa
Amino Acids	572 aa
UniProt ID	Q9NPD8
NCBI Gene ID	6404
Ensembl ID	ENSG00000110851
OMIM	607469
GeneCards	SLC6A13
Human Protein Atlas	SLC6A13
Associated Diseases	Carotid Paragangliomas, Metabolite Levels, Neurological Disorders
KG Connections	5 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: SLC6A13 — AlphaFold Q9NPD8 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

SLC6A13 Gene

gene · 1602 words

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Pathway Diagram

flowchart TD
    SLC6A13(["SLC6A13"])
    GABA["GABA"]
    Metabolite_Levels("Metabolite Levels")
    GAT1(["GAT1"])
    Neurological_Disorders["Neurological Disorders"]
    Carotid_Paragangliomas["Carotid Paragangliomas"]
    neurodegeneration["neurodegeneration"]

    SLC6A13 -->|"associated with"| GABA
    SLC6A13 -->|"associated with"| Metabolite_Levels
    SLC6A13 -->|"associated with"| GAT1
    SLC6A13 -->|"implicated in"| Neurological_Disorders
    SLC6A13 -->|"associated with"| Carotid_Paragangliomas
    SLC6A13 -->|"implicated in"| neurodegeneration

    style SLC6A13 fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff

Outgoing (5)

Target	Relation	Type	Str
Metabolite Levels	associated_with	phenotype	0.80
GABA	associated_with	entity	0.80
GAT1	associated_with	gene	0.70
Neurological Disorders	implicated_in	disease	0.60
Carotid Paragangliomas	associated_with	disease	0.60

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SLC6A13 in their description or question text

No additional research found