Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MYOC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | MYOC |
| Key Genes/Proteins | Actin, ALZHEIMER, ALZHEIMER DISEASE, AND, APOE, APOE REGULATORY REGIONS |
| Related Diseases | Als, ALS, Alzheimer, Glaucoma |
| Related Pathways | autophagy pathway, Lipid Metabolism |
graph TD
MYOC["MYOC"]
MYOC -->|"activates"| Alzheimer["Alzheimer"]
MYOC -->|"activates"| Neuropathy["Neuropathy"]
MYOC -->|"activates"| ALS["ALS"]
MYOC -->|"activates"| Glaucoma["Glaucoma"]
MYOC -->|"activates"| Als["Als"]
MYOC -->|"activates"| APOE["APOE"]
MYOC -->|"activates"| ALZHEIMER_DISEASE["ALZHEIMER DISEASE"]
MYOC -->|"activates"| ALZHEIMER["ALZHEIMER"]
APOE_REGULATORY_REGIONS["APOE REGULATORY REGIONS"] -->|"interacts"| MYOC
APOE -->|"activates"| MYOC
GLAUCOMA["GLAUCOMA"] -->|"activates"| MYOC| Target | Relation | Type | Str |
|---|---|---|---|
| Alzheimer | activates | disease | 0.65 |
| Neuropathy | activates | disease | 0.65 |
| ALS | activates | disease | 0.65 |
| Glaucoma | activates | disease | 0.65 |
| Als | activates | disease | 0.65 |
| ALZHEIMER | activates | gene | 0.60 |
| AND | activates | gene | 0.60 |
| Lipid Metabolism | activates | pathway | 0.60 |
| GLAUCOMA | activates | gene | 0.60 |
| Neuron | activates | cell_type | 0.60 |
| Actin | activates | protein | 0.60 |
| APOE | activates | gene | 0.60 |
| ALZHEIMER DISEASE | activates | gene | 0.60 |
| OPTN | activates | gene | 0.60 |
| autophagy pathway | participates_in | pathway | 0.60 |
| Neuron | expressed_in | cell_type | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| APOE | activates | gene | 0.60 |
| APOE REGULATORY REGIONS | interacts_with | gene | 0.60 |
| LOXL1 | activates | gene | 0.60 |
| GLAUCOMA | activates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning MYOC in their description or question text
No additional research found