gene

mef2d

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about mef2d: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

19Connections

0Hypotheses

0Analyses

14Outgoing

5Incoming

0Experiments

0Debates

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🧬 Gene Info

Gene Symbol	MEF2D
Full Name	Myocyte Enhancer Factor 2D
Aliases	Page for MEF2D Protein
Chromosome	5q14.1
Protein Type	Transcription Factor
Function	Neurotransmitter-related genes
Primary Expression	Cortex, Hippocampus, Striatum, Cerebellum, Substantia Nigra
Molecular Weight	55.4 kDa
Amino Acids	507 aa
Exons	13
Pathways	MAPK
UniProt ID	Q01484
NCBI Gene ID	4209
Ensembl ID	ENSG00000105509
OMIM	600663
GeneCards	MEF2D
Human Protein Atlas	MEF2D
Associated Diseases	Parkinson's Disease, Huntington's Disease, Alzheimer's Disease
Interactions	APOPTOSIS, EP300, MMP9
KG Connections	19 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: mef2d — AlphaFold Q01484 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

MEF2D — Myocyte Enhancer Factor 2D

gene · 1437 words

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Pathway Diagram

graph TD
    MEF2D["MEF2D"]
    MEF2D -->|"regulates"| HDAC7["HDAC7"]
    MEF2D -->|"target for"| Aging["Aging"]
    MEF2D -->|"target for"| Cardiovascular["Cardiovascular"]
    MEF2D -->|"activates"| Leukemia["Leukemia"]
    MEF2D -->|"inhibits"| MMP9["MMP9"]
    MEF2D -->|"activates"| APOPTOSIS["APOPTOSIS"]
    MEF2D -->|"activates"| Apoptosis["Apoptosis"]
    MEF2D -->|"implicated in"| neurodegeneration["neurodegeneration"]
    EP300["EP300"] -->|"activates"| MEF2D
    MMP9 -->|"inhibits"| MEF2D
    APOPTOSIS -->|"activates"| MEF2D

Outgoing (14)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:MEF2D	data_in	dataset_row	0.00
HDAC9	associated_with	gene	0.90
HDAC7	regulates	protein	0.80
Leukemia	activates	disease	0.65
Aging	therapeutic_target	disease	0.65
Cardiovascular	therapeutic_target	disease	0.65
Apoptosis	activates	pathway	0.60
UFL1	associated_with	gene	0.60
oxidative stress response	participates_in	pathway	0.60
STAT6	associated_with	gene	0.60
APOPTOSIS	activates	gene	0.60
MMP9	inhibits	gene	0.60
GENE MUTATIONS	associated_with	gene	0.60
Epigenetic	associated_with	pathway	0.60

Incoming (5)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:MEF2D	data_in	dataset_row	0.00
APOPTOSIS	activates	gene	0.60
MMP9	inhibits	gene	0.60
LRP1	associated_with	gene	0.60
EP300	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning mef2d in their description or question text

No additional research found