protein

GLUTAMINE SYNTHETASE

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GLUTAMINE SYNTHETASE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

15Connections

0Hypotheses

0Analyses

13Outgoing

2Incoming

0Experiments

0Debates

Summary

Page for Glutamine Synthetase Protein

View on Wiki →

No AI portrait yet

🔬 Protein Info

Gene Symbol	GLUTAMINE SYNTHETASE
Molecular Weight	49.2 kDa
Amino Acids	373 aa
Pathways	Cholesterol
Associated Diseases	disease
Interactions	BDNF, HMGCR
KG Connections	15 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Pathway Diagram

graph TD
    GLUTAMINE_SYNTHETASE["GLUTAMINE SYNTHETASE"]
    GLUTAMINE_SYNTHETASE -->|"inhibits"| HMGCR["HMGCR"]
    GLUTAMINE_SYNTHETASE -->|"inhibits"| Genes["Genes"]
    GLUTAMINE_SYNTHETASE -->|"inhibits"| Cholesterol["Cholesterol"]
    GLUTAMINE_SYNTHETASE -->|"inhibits"| Neuron["Neuron"]
    GLUTAMINE_SYNTHETASE -->|"inhibits"| MOTOR_NEURONS["MOTOR NEURONS"]
    GLUTAMINE_SYNTHETASE -->|"inhibits"| Oligodendrocyte["Oligodendrocyte"]
    GLUTAMINE_SYNTHETASE -->|"inhibits"| NEURONS["NEURONS"]
    GLUTAMINE_SYNTHETASE -->|"inhibits"| OLIGODENDROCYTES["OLIGODENDROCYTES"]
    BDNF["BDNF"] -->|"inhibits"| GLUTAMINE_SYNTHETASE

Outgoing (13)

Target	Relation	Type	Str
HMGCR	inhibits	gene	0.50
Cholesterol	inhibits	pathway	0.50
Neuron	inhibits	cell_type	0.50
MOTOR NEURONS	inhibits	concept	0.50
Oligodendrocyte	inhibits	cell_type	0.50
NEURONS	inhibits	concept	0.50
OLIGODENDROCYTES	inhibits	concept	0.50
MOTOR NEURON	inhibits	concept	0.50
GLUTAMATE	inhibits	concept	0.50
disease	associated_with	disease	0.50
Proteins	associated_with	protein	0.50
GLUTAMATE	associated_with	concept	0.50
SYNAPSE	associated_with	concept	0.50

Incoming (2)

Source	Relation	Type	Str
AQUAPORIN-4	associated_with	gene	0.50
BDNF	inhibits	gene	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning GLUTAMINE SYNTHETASE in their description or question text

No additional research found