protein

FGF-2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about FGF-2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

17Connections

0Hypotheses

0Analyses

14Outgoing

3Incoming

0Experiments

0Debates

Summary

Page for FGF-2 Protein (bFGF)

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🔬 Protein Info

Gene Symbol	FGF
Pathways	oxidative stress response, TGF-beta signaling, Angiogenesis, Oxidative Stress, Immune Response
GeneCards	FGF
Human Protein Atlas	FGF
Associated Diseases	Glioblastoma
Interactions	Actin, Akt, AND, APOPTOSIS, App, ASTROCYTE
KG Connections	242 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

FGF-2 Protein (bFGF)

protein · 1475 words

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Pathway Diagram

graph TD
    FGF_2["FGF-2"]
    FGF_2 -->|"activates"| AUTOPHAGY["AUTOPHAGY"]
    FGF_2 -->|"activates"| SPTLC1["SPTLC1"]
    FGF_2 -->|"activates"| CERS2["CERS2"]
    FGF_2 -->|"activates"| apoptosis["apoptosis"]
    FGF_2 -->|"activates"| FIBROSIS["FIBROSIS"]
    FGF_2 -->|"activates"| Macrophage["Macrophage"]
    FGF_2 -->|"activates"| Epithelial_Cell["Epithelial Cell"]
    FGF_2 -->|"activates"| Fibroblast["Fibroblast"]
    Autophagy["Autophagy"] -->|"activates"| FGF_2
    TGF__1["TGF-Beta1"] -->|"activates"| FGF_2

Outgoing (14)

Target	Relation	Type	Str
neurotrophin signaling	participates_in	pathway	0.55
astrocytes	expressed_in	cell_type	0.55
SPTLC1	activates	gene	0.50
TGF-Β1	co_discussed	protein	0.50
WAS	co_discussed	protein	0.50
CERS2	activates	gene	0.50
apoptosis	activates	process	0.50
AUTOPHAGY	activates	gene	0.50
Macrophage	activates	cell_type	0.50
Epithelial Cell	activates	cell_type	0.50
Fibroblast	activates	cell_type	0.50
Pulmonary Fibrosis	activates	disease	0.50
FIBROSIS	activates	disease	0.50
GENES	co_discussed	gene	0.50

Incoming (3)

Source	Relation	Type	Str
BDNF	activates	gene	0.55
Autophagy	activates	process	0.50
TGF-Β1	activates	protein	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning FGF-2 in their description or question text

No additional research found