concept

ERBB1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ERBB1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

19Connections

0Hypotheses

0Analyses

14Outgoing

5Incoming

0Experiments

0Debates

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💡 Concept Info

Name	ERBB1
Key Genes/Proteins	ATXN3, B4GALNT1, BST1, CR2, GPNMB, IL34
Related Diseases	ALS, Alzheimer's disease, Alzheimer's Disease, Alzheimer'S Disease, neurodegeneration
Related Pathways	oxidative stress response

Pathway Diagram

graph TD
    ERBB1[ERBB1]
    ERBB1 -->|target for| Alzheimer_S_Disease[Alzheimer'S Disease]
    ERBB1 -->|target for| Alzheimer_s_Disease[Alzheimer's Disease]
    ERBB1 -->|causes| GPNMB[GPNMB]
    ERBB1 -->|causes| IL34[IL34]
    ERBB1 -->|causes| PILRA[PILRA]
    ERBB1 -->|causes| SHARPIN[SHARPIN]
    ERBB1 -->|causes| STX6[STX6]
    ERBB1 -->|causes| TREM2[TREM2]
    ERBB1 -->|causes| neurodegeneration[neurodegeneration]
    ERBB1 -->|causes| Alzheimer_s_disease[Alzheimer's disease]
    ATXN3[ATXN3] -->|causes| ERBB1
    BST1[BST1] -->|causes| ERBB1
    CR2[CR2] -->|causes| ERBB1
    B4GALNT1[B4GALNT1] -->|causes| ERBB1
    benchmark_ot_ad_answer_key_ERB[benchmark_ot_ad_answer_key:ERBB1] -->|data_in| ERBB1

Outgoing (14)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:ERBB1	data_in	dataset_row	0.00
Alzheimer'S Disease	therapeutic_target	disease	0.85
Alzheimer's Disease	therapeutic_target	disease	0.80
oxidative stress response	participates_in	pathway	0.60
Alzheimer's disease	causes	disease	0.60
Parkinson's disease	causes	disease	0.60
ALS	causes	disease	0.60
IL34	causes	gene	0.60
PILRA	causes	gene	0.60
SHARPIN	causes	gene	0.60
GPNMB	causes	gene	0.60
TREM2	causes	gene	0.60
neurodegeneration	causes	disease	0.60
STX6	causes	gene	0.60

Incoming (5)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:ERBB1	data_in	dataset_row	0.00
B4GALNT1	causes	gene	0.60
ATXN3	causes	gene	0.60
BST1	causes	gene	0.60
CR2	causes	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning ERBB1 in their description or question text

No additional research found