concept

EMT

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about EMT: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

19Connections

0Hypotheses

0Analyses

5Outgoing

14Incoming

0Experiments

0Debates

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💡 Concept Info

Name	EMT
Key Genes/Proteins	C3, DVL3, IL6, Netrin-1, NETRIN-1, NETRIN1
Related Diseases	Cancer, Fibrosis, METASTASIS
Related Pathways	Netrin-1 Inhibition

Pathway Diagram

graph TD
    EMT[EMT]
    EMT -->|contributes to| Cancer[Cancer]
    EMT -->|activates| METASTASIS[METASTASIS]
    EMT -->|contributes to| Fibrosis[Fibrosis]
    Netrin_1[Netrin-1] -->|regulates| EMT
    Netrin_1_Inhibition[Netrin-1 Inhibition] -->|inhibits| EMT
    NTN1[NTN1] -->|promotes| EMT
    Pharmacological_targeting[Pharmacological targeting] -->|inhibits| EMT
    NETRIN1[NETRIN1] -->|inhibits| EMT
    TGFB1[TGFB1] -->|enhances| EMT
    NETRIN_1[NETRIN-1] -->|inhibits| EMT
    C3[C3] -->|activates| EMT
    SRC[SRC] -->|activates| EMT

Outgoing (5)

Target	Relation	Type	Str
Cancer	promotes	disease	0.90
Cancer	contributes_to	disease	0.90
METASTASIS	activates	phenotype	0.72
Fibrosis	contributes_to	disease	0.70
PACLITAXEL	associated_with	drug	0.45

Incoming (14)

Source	Relation	Type	Str
Netrin-1	regulates	protein	0.95
NTN1	promotes	protein	0.95
Netrin-1 Inhibition	inhibits	mechanism	0.95
Pharmacological targeting	inhibits	drug	0.92
NETRIN1	inhibits	protein	0.90
NTN1	inhibits	entity	0.90
TGFB1	enhances	gene	0.90
DVL3	associated_with	gene	0.80
NETRIN-1	inhibits	protein	0.80
IL6	enhances	gene	0.80
C3	activates	protein	0.64
LUTEOLIN	inhibits	drug	0.64
SRC	activates	protein	0.64
CARBOPLATIN	associated_with	drug	0.45

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning EMT in their description or question text

No additional research found