Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about COX17: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | COX17 |
| Key Genes/Proteins | ALZHEIMER, ALZHEIMER'S DISEASE, AND, APP, APP/PS1, ATP5MC1 |
| Related Diseases | Als, Alzheimer |
| Related Pathways | mitochondrial function, oxidative phosphorylation |
graph TD
COX17[COX17]
COX17 -->|regulates| oxidative_phosphorylation[oxidative phosphorylation]
COX17 -->|activates| Als[Als]
COX17 -->|regulates| Alzheimer[Alzheimer]
COX17 -->|activates| NDUFB1[NDUFB1]
COX17 -->|activates| Microglia[Microglia]
COX17 -->|participates in| mitochondrial_function[mitochondrial function]
COX17 -->|data_in| benchmark_ot_ad_answer_key_COX[benchmark_ot_ad_answer_key:COX17]
APP[APP] -->|activates| COX17
ATP5MC1[ATP5MC1] -->|activates| COX17
ALZHEIMER[ALZHEIMER] -->|regulates| COX17
AND[AND] -->|activates| COX17
MICROGLIA[MICROGLIA] -->|activates| COX17
ALZHEIMER_S_DISEASE[ALZHEIMER'S DISEASE] -->|regulates| COX17
APP_PS1[APP/PS1] -->|activates| COX17
benchmark_ot_ad_answer_key_COX -->|data_in| COX17| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:COX17 | data_in | dataset_row | 0.00 |
| oxidative phosphorylation | regulates | pathway | 0.70 |
| Als | activates | disease | 0.65 |
| Alzheimer | regulates | disease | 0.65 |
| mitochondrial function | participates_in | pathway | 0.60 |
| NDUFB1 | activates | gene | 0.60 |
| Microglia | activates | cell_type | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:COX17 | data_in | dataset_row | 0.00 |
| AND | activates | gene | 0.60 |
| APP | activates | gene | 0.60 |
| ATP5MC1 | activates | gene | 0.60 |
| ALZHEIMER | regulates | gene | 0.60 |
| MICROGLIA | activates | gene | 0.60 |
| ALZHEIMER'S DISEASE | regulates | gene | 0.60 |
| APP/PS1 | activates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning COX17 in their description or question text
No additional research found