Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CHRFAM7A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | CHRFAM7A |
| Key Genes/Proteins | A2M, BCHE, CHRNA7, CNTN1, DNA, ESR1 |
| Related Diseases | depression, schizophrenia |
graph TD
CHRFAM7A[CHRFAM7A]
CHRFAM7A -->|implicated in| schizophrenia[schizophrenia]
CHRFAM7A -->|inhibits| CHRNA7[CHRNA7]
CHRFAM7A -->|expressed in| neurons[neurons]
CHRFAM7A -->|interacts| CNTN1[CNTN1]
CHRFAM7A -->|interacts| ESR1[ESR1]
CHRFAM7A -->|interacts| GABRB3[GABRB3]
CHRFAM7A -->|interacts| MAPT[MAPT]
CHRFAM7A -->|interacts| PSEN1[PSEN1]
CHRFAM7A -->|interacts| SCARB2[SCARB2]
A2M[A2M] -->|interacts| CHRFAM7A
BCHE[BCHE] -->|interacts| CHRFAM7A
benchmark_ot_ad_answer_key_CHR[benchmark_ot_ad_answer_key:CHRFAM7A] -->|data_in| CHRFAM7A| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:CHRFAM7A | data_in | dataset_row | 0.00 |
| schizophrenia | implicated_in | disease | 0.80 |
| CHRNA7 | inhibits | gene | 0.70 |
| neurons | expressed_in | cell_type | 0.70 |
| CHRNA7 | expressed_in | gene | 0.70 |
| CHRNA7 | associated_with | gene | 0.70 |
| depression | expressed_in | disease | 0.60 |
| schizophrenia | expressed_in | disease | 0.60 |
| schizophrenia | associated_with | disease | 0.60 |
| SOX2 | expressed_in | gene | 0.60 |
| ubiquitin-proteasome | participates_in | pathway | 0.60 |
| stem cells | expressed_in | cell_type | 0.60 |
| RNA | inhibits | gene | 0.60 |
| CHRNA7 | protects_against | gene | 0.60 |
| CHRNA7 | interacts_with | gene | 0.60 |
| schizophrenia | interacts_with | disease | 0.60 |
| DNA | interacts_with | gene | 0.60 |
| ESR1 | interacts_with | gene | 0.60 |
| GABRB3 | interacts_with | gene | 0.60 |
| MAPT | interacts_with | gene | 0.60 |
| PSEN1 | interacts_with | gene | 0.60 |
| SCARB2 | interacts_with | gene | 0.60 |
| TFAM | interacts_with | gene | 0.60 |
| TREM2 | interacts_with | gene | 0.60 |
| UCHL1 | interacts_with | gene | 0.60 |
| CNTN1 | interacts_with | gene | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:CHRFAM7A | data_in | dataset_row | 0.00 |
| A2M | interacts_with | gene | 0.60 |
| BCHE | interacts_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity