gene

BAI1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about BAI1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

12Connections
0Hypotheses
0Analyses
5Outgoing
7Incoming
0Experiments
0Debates

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🧬 Gene Info
Gene SymbolBAI1
Chromosome8q24.12
Protein TypeReceptor
Functionis a member of the adhesion G protein-coupled receptor (GPCR) family and contains multiple functional domains that mediate its interactions with various cellular partners.
Molecular Weight175 kDa
Amino Acids584 aa
Exons31
PathwaysComplement
Ensembl IDENSG00000181789
GeneCardsBAI1
Human Protein AtlasBAI1
BAI1-AFull-length isoform with all functional domains
BAI1-BTruncated variant lacking part of extracellular domain
BAI1-V1Brain-specific alternative splice isoform
BAI1-V2Endothelial cell-enriched isoform
Associated Diseasesneurodegeneration
InteractionsEGF, RTN4, SYNAPSE
KG Connections12 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

bai1

gene · 2283 words

BAI1 Protein

protein · 608 words

Pathway Diagram

graph TD
    BAI1["BAI1"]
    Ms{"Ms"}
    BAI1 -->|"interacts with"| Ms
    RTN4["RTN4"]
    BAI1 -->|"interacts with"| RTN4
    Complement(["Complement"])
    BAI1 -->|"regulates"| Complement
    neurodegeneration["neurodegeneration"]
    BAI1 -->|"implicated in"| neurodegeneration
    CD44["CD44"]
    CD44 -->|"associated with"| BAI1
    COMPLEMENT["COMPLEMENT"]
    COMPLEMENT -->|"regulates"| BAI1
    C1Q["C1Q"]
    C1Q -->|"associated with"| BAI1
    MET["MET"]
    MET -->|"associated with"| BAI1
    ADCY5["ADCY5"]
    ADCY5 -->|"associated with"| BAI1
    style BAI1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (5)

TargetRelationTypeStr
Msinteracts_withdisease0.65
Complementregulatespathway0.60
RTN4interacts_withgene0.60
microgliaexpressed_incell_type0.55
EGFinhibitsgene0.55

Incoming (7)

SourceRelationTypeStr
CD44associated_withgene0.60
C1Qassociated_withgene0.60
METassociated_withgene0.60
ADCY5associated_withgene0.60
SYNAPSEinteracts_withgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning BAI1 in their description or question text

No additional research found