Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ACUPUNCTURE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
graph TD
ACUPUNCTURE[ACUPUNCTURE]
ACUPUNCTURE -->|activates| MCH[MCH]
ACUPUNCTURE -->|treats| Parkinson_S_Disease[Parkinson'S Disease]
ACUPUNCTURE -->|regulates| autophagy[autophagy]
ACUPUNCTURE -->|regulates| LC3[LC3]
ACUPUNCTURE -->|regulates| Beclin1[Beclin1]
ACUPUNCTURE -->|upregulates| BDNF[BDNF]
ACUPUNCTURE -->|regulates| miRNAs[miRNAs]
ACUPUNCTURE -->|regulates| PI3K_AKT_pathway[PI3K/AKT pathway]
ACUPUNCTURE -->|inhibits| neuroinflammation[neuroinflammation]
ACUPUNCTURE -->|regulates| Bax[Bax]
BDNF -->|interacts| ACUPUNCTURE| Target | Relation | Type | Str |
|---|---|---|---|
| Parkinson'S Disease | treats | disease | 0.95 |
| MCH | activates | protein | 0.95 |
| autophagy | regulates | pathway | 0.90 |
| BDNF | upregulates | gene | 0.80 |
| miRNAs | regulates | gene | 0.80 |
| LC3 | regulates | protein | 0.80 |
| Beclin1 | regulates | protein | 0.80 |
| Alzheimer's disease | treats | disease | 0.70 |
| Alzheimer's disease | treats | disease | 0.70 |
| PI3K/AKT | regulates | pathway | 0.70 |
| Bax | regulates | protein | 0.70 |
| BCL2 | regulates | protein | 0.70 |
| Parkinson's disease | treats | disease | 0.70 |
| dopaminergic neurons | activates | cell_type | 0.70 |
| apoptosis | inhibits | process | 0.70 |
| PI3K/AKT pathway | regulates | pathway | 0.70 |
| neuroinflammation | inhibits | process | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| BDNF | interacts_with | gene | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning ACUPUNCTURE in their description or question text
No additional research found