Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about arid1b: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | ARID1B |
| Chromosome | 6q25.3 |
| Function | BAF chromatin remodeling complex subunit |
| Amino Acids | 2236 aa |
| Exons | 20 |
| Pathways | Epigenetic, Wnt, epigenetic regulation |
| Ensembl ID | ENSG00000049618 |
| GeneCards | ARID1B |
| Human Protein Atlas | ARID1B |
| Associated Diseases | Als, Autism, ALS, autism spectrum disorder |
| Interactions | PVALB |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
ARID1B["ARID1B"]
ARID1B -->|"causes"| Als["Als"]
ARID1B -->|"causes"| Autism["Autism"]
ARID1B -->|"causes"| ALS["ALS"]
ARID1B -->|"regulates"| GABA["GABA"]
ARID1B -->|"regulates"| Epigenetic["Epigenetic"]
ARID1B -->|"regulates"| Wnt["Wnt"]
ARID1B -->|"regulates"| WNT["WNT"]
ARID1B -->|"regulates"| PVALB["PVALB"]
PVALB -->|"regulates"| ARID1B
GABA -->|"regulates"| ARID1B
AUTISM["AUTISM"] -->|"causes"| ARID1B| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:ARID1B | data_in | dataset_row | 0.00 |
| Autism | causes | disease | 0.65 |
| Als | causes | disease | 0.65 |
| ALS | causes | disease | 0.65 |
| Neural Progenitor | regulates | cell_type | 0.60 |
| WNT | regulates | gene | 0.60 |
| GABA | regulates | gene | 0.60 |
| AND | regulates | gene | 0.60 |
| PVALB | regulates | gene | 0.60 |
| Epigenetic | regulates | pathway | 0.60 |
| Wnt | regulates | pathway | 0.60 |
| autism spectrum disorder | causes | disease | 0.60 |
| autism spectrum disorder | associated_with | disease | 0.60 |
| epigenetic regulation | participates_in | pathway | 0.60 |
| stem cells | expressed_in | cell_type | 0.60 |
| Rb | causes | protein | 0.60 |
| PVALB | activates | gene | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:ARID1B | data_in | dataset_row | 0.00 |
| PVALB | regulates | gene | 0.60 |
| GABA | regulates | gene | 0.60 |
| AUTISM | causes | disease | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning arid1b in their description or question text
No additional research found