gene

als9

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about als9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

21Connections

0Hypotheses

0Analyses

14Outgoing

7Incoming

0Experiments

0Debates

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🧬 Gene Info

Gene Symbol	ALS9
Full Name	Amyotrophic Lateral Sclerosis 9
Aliases	Page for ALS9
Chromosome	14q11.2
Protein Type	Secreted ribonuclease
Function	is a genetic subtype of familial amyotrophic lateral sclerosis caused by mutations in the ANG gene (Angiogenin).
Primary Expression	Broad, high in liver, brain, and motor neurons
Molecular Weight	14.9 kDa
Amino Acids	147 aa
Pathways	PI3K
UniProt ID	P03950
Ensembl ID	ENSG00000100939
OMIM	105400
GeneCards	ALS9
Human Protein Atlas	ALS9
Associated Diseases	Als, Amyotrophic Lateral Sclerosis, Glaucoma
KG Connections	21 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: als9 — AlphaFold P03950 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

ALS9 - Amyotrophic Lateral Sclerosis 9

gene · 1321 words

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Pathway Diagram

graph TD
    ALS9["ALS9"]
    ALS9 -->|"implicated in"| neurodegeneration["neurodegeneration"]
    ALS9 ---|"associated"| Als["Als"]
    ALS9 ---|"associated"| Glaucoma["Glaucoma"]
    ALS9 ---|"associated"| Amyotrophic_Lateral_Sclerosis["Amyotrophic Lateral Sclerosis"]
    ALS9 ---|"associated"| TARDBP["TARDBP"]
    ALS9 ---|"associated"| ALS7["ALS7"]
    ALS2["ALS2"] ---|"associated"| ALS9
    FIG4["FIG4"] ---|"associated"| ALS9
    FUS["FUS"] ---|"associated"| ALS9
    ALS8["ALS8"] ---|"associated"| ALS9
    ALSIN["ALSIN"] ---|"associated"| ALS9

Outgoing (14)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:ALS9	data_in	dataset_row	0.00
Als	associated_with	disease	0.65
Glaucoma	associated_with	disease	0.65
Amyotrophic Lateral Sclerosis	associated_with	disease	0.65
DNA	associated_with	gene	0.60
ALS	associated_with	gene	0.60
GENE MUTATIONS	associated_with	gene	0.60
AMYOTROPHIC LATERAL SCLEROSIS	associated_with	gene	0.60
GENES	associated_with	gene	0.60
MOTOR NEURONS	associated_with	gene	0.60
TARDBP	associated_with	gene	0.60
ALS7	associated_with	gene	0.60
ALS10	associated_with	gene	0.60
SOD1	associated_with	gene	0.60

Incoming (7)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:ALS9	data_in	dataset_row	0.00
ALS2	associated_with	gene	0.60
FIG4	associated_with	gene	0.60
FUS	associated_with	gene	0.60
ALS8	associated_with	gene	0.60
ALSIN	associated_with	gene	0.60
ALS4	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning als9 in their description or question text

No additional research found