gene

als7

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about als7: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

21Connections

0Hypotheses

0Analyses

12Outgoing

9Incoming

0Experiments

0Debates

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🧬 Gene Info

Gene Symbol	ALS7
Full Name	ALS7 - Amyotrophic Lateral Sclerosis 7
Aliases	Page for ALS7
Chromosome	20p13
Protein Type	Gene
Function	is a genetic locus associated with familial amyotrophic lateral sclerosis (FALS)
Gene Type	Protein-coding (exact gene product under investigation)
OMIM	607350
GeneCards	ALS7
Human Protein Atlas	ALS7
Inheritance Pattern	Autosomal dominant
Central nervous system	Motor cortex, spinal cord (motor neurons), hippocampus
Peripheral tissues	Various organs with highest expression in nervous system tissue
Cellular localization	Cytoplasmic and nuclear compartments
Associated Diseases	Als, Amyotrophic Lateral Sclerosis, Glaucoma
KG Connections	21 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

ALS7 - Amyotrophic Lateral Sclerosis 7

gene · 883 words

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Pathway Diagram

graph TD
    ALS7["ALS7"]
    ALS7 -->|"implicated in"| neurodegeneration["neurodegeneration"]
    ALS7 ---|"associated"| Als["Als"]
    ALS7 ---|"associated"| Glaucoma["Glaucoma"]
    ALS7 ---|"associated"| Amyotrophic_Lateral_Sclerosis["Amyotrophic Lateral Sclerosis"]
    ALS7 ---|"associated"| ALS["ALS"]
    ALS7 ---|"associated"| GENES["GENES"]
    ALS2["ALS2"] ---|"associated"| ALS7
    FIG4["FIG4"] ---|"associated"| ALS7
    FUS["FUS"] ---|"associated"| ALS7
    ALS8["ALS8"] ---|"associated"| ALS7
    ALSIN["ALSIN"] ---|"associated"| ALS7

Outgoing (12)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:ALS7	data_in	dataset_row	0.00
Als	associated_with	disease	0.65
Glaucoma	associated_with	disease	0.65
Amyotrophic Lateral Sclerosis	associated_with	disease	0.65
DNA	associated_with	gene	0.60
ALS	associated_with	gene	0.60
GENE MUTATIONS	associated_with	gene	0.60
AMYOTROPHIC LATERAL SCLEROSIS	associated_with	gene	0.60
GENES	associated_with	gene	0.60
MOTOR NEURONS	associated_with	gene	0.60
ALS10	associated_with	gene	0.60
SOD1	associated_with	gene	0.60

Incoming (9)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:ALS7	data_in	dataset_row	0.00
ALS2	associated_with	gene	0.60
FIG4	associated_with	gene	0.60
FUS	associated_with	gene	0.60
ALS8	associated_with	gene	0.60
ALSIN	associated_with	gene	0.60
ALS4	associated_with	gene	0.60
ALS9	associated_with	gene	0.60
TARDBP	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning als7 in their description or question text

No additional research found