Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about WDR91: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | WDR91 |
| Related Diseases | Endosomal Accumulation, neurodegeneration, Neurodegeneration |
| Related Pathways | autophagy pathway |
graph TD
WDR91[WDR91]
WDR91 -->|causes| neurodevelopmental_disorder[neurodevelopmental disorder]
WDR91 -->|regulates| Endosomal_Trafficking[Endosomal Trafficking]
WDR91 -->|regulates| Lysosomal_Function[Lysosomal Function]
WDR91 -->|modulates| Endosomal_Maturation[Endosomal Maturation]
WDR91 -->|modulates| Lysosome_Homeostasis[Lysosome Homeostasis]
WDR91 -->|regulates| Autophagy[Autophagy]
WDR91 -->|interacts| RAB7[RAB7]
WDR91 -->|interacts| WDR81[WDR81]
WDR91 -->|regulates| endosomal_trafficking[endosomal trafficking]
WDR91 -->|regulates| lysosomal_function[lysosomal function]
benchmark_ot_ad_answer_key_WDR[benchmark_ot_ad_answer_key:WDR91] -->|data_in| WDR91| Target | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:WDR91 | data_in | dataset_row | 0.00 |
| Endosomal Maturation | modulates | process | 0.95 |
| Endosomal Trafficking | regulates | process | 0.95 |
| Lysosomal Function | regulates | process | 0.95 |
| Lysosome Homeostasis | modulates | process | 0.95 |
| Autophagy | regulates | process | 0.95 |
| neurodevelopmental disorder | causes | disease | 0.95 |
| Neurodegeneration | associated_with | disease | 0.90 |
| lysosomal function | regulates | process | 0.90 |
| RAB7 | interacts_with | protein | 0.90 |
| endosomal trafficking | regulates | process | 0.90 |
| WDR81 | interacts_with | protein | 0.90 |
| Neurodevelopmental Disorder | associated_with | disease | 0.90 |
| Endosomal Accumulation | causes | phenotype | 0.85 |
| PI3K | modulates | protein | 0.85 |
| cargo degradation | involved_in | process | 0.85 |
| autophagy | regulates | process | 0.85 |
| lysosome homeostasis | modulates | process | 0.85 |
| neurodegeneration | associated_with | disease | 0.60 |
| autophagy pathway | participates_in | pathway | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| benchmark_ot_ad_answer_key:WDR91 | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning WDR91 in their description or question text
No additional research found