Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about TRALOKINUMAB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | TRALOKINUMAB |
graph TD
TRALOKINUMAB[TRALOKINUMAB]
TRALOKINUMAB -->|inhibits| IL13[IL13]
TRALOKINUMAB -->|treats| Atopic_Dermatitis[Atopic Dermatitis]
TRALOKINUMAB -->|inhibits| IL_13[IL-13]
TRALOKINUMAB -->|downregulates| CCL17[CCL17]
TRALOKINUMAB -->|downregulates| PERP[PERP]
TRALOKINUMAB -->|downregulates| IL31[IL31]
TRALOKINUMAB -->|downregulates| IFNG[IFNG]
TRALOKINUMAB -->|downregulates| IL4R[IL4R]
TRALOKINUMAB -->|upregulates| CLDN1[CLDN1]
TRALOKINUMAB -->|upregulates| LOR[LOR]| Target | Relation | Type | Str |
|---|---|---|---|
| IL13 | inhibits | protein | 0.99 |
| Atopic Dermatitis | treats | disease | 0.95 |
| IL-13 | inhibits | protein | 0.95 |
| CCL17 | downregulates | protein | 0.92 |
| PERP | downregulates | biomarker | 0.92 |
| IL4R | downregulates | gene | 0.90 |
| IL31 | downregulates | gene | 0.90 |
| IFNG | downregulates | gene | 0.90 |
| LOR | upregulates | gene | 0.88 |
| CLDN1 | upregulates | gene | 0.88 |
| CCL17/TARC | downregulates | biomarker | 0.85 |
| IgE | downregulates | protein | 0.85 |
| Epidermal Thickness | modulates | phenotype | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning TRALOKINUMAB in their description or question text
No additional research found