| Gene Symbol | TOR1A |
| Full Name | Torsin-1A |
| Chromosome | 9q34.11 |
| Function | is a glutamate deletion (ΔE302/303) that causes early-onset generalized dystonia (DYT1), one of the most common hereditary movement disorders [2](https://pubmed. |
| Subcellular Localization | Torsin-1A exhibits distinctive subcellular localization: |
| Molecular Weight | 38 kDa |
| Amino Acids | 332 aa |
| UniProt ID | [O95631](https://www.uniprot.org/uniprot/O95631) |
| Ensembl ID | ENSG00000136827 |
| OMIM | 605204 |
| GeneCards | TOR1A |
| Human Protein Atlas | TOR1A |
| N-terminal domain | Signal peptide directing ER localization |
| ATPase domain | Classic AAA+Walker A (P-loop) and Walker B motifs |
| C-terminal region | Involved in protein-protein interactions |
| Associated Diseases | Als |
| KG Connections | 10 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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