| Gene Symbol | TGFBR2 |
| Full Name | Transforming Growth Factor Beta Receptor 2 |
| Aliases | TGFBR2PROTEIN |
| Chromosome | 3p22.1 |
| Function | TGFBR2 (Transforming Growth Factor Beta Receptor 2) encodes the type II TGF-β receptor, a transmembrane serine/threonine kinase that is essential for TGF-β signaling. |
| Primary Expression | the brain: |
| Pathways | TGF-β, TGF-β signaling, PI3K, MAPK |
| UniProt ID | [P37173](https://www.uniprot.org/uniprot/P37173) |
| Ensembl ID | ENSG00000163513 |
| GeneCards | TGFBR2 |
| Human Protein Atlas | TGFBR2 |
| Neuronal Survival | TGF-β is a potent neurotrophic factor |
| Synaptic Plasticity | TGF-β modulates long-term potentiation and depression |
| Neuroprotection | TGF-β protects against various toxins |
| Differentiation | TGF-β influences neural progenitor differentiation |
| Associated Diseases | Als, Cancer, Carcinoma, Colorectal Cancer, Gastric Cancer |
| Interactions | AND, GENES, PIEZO1, SMAD2, TGF, TGFBR1 |
| KG Connections | 76 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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