| Gene Symbol | SOX2 |
| Full Name | SRY-Box Transcription Factor 2 |
| Chromosome | 3q26.33 |
| Protein Type | Transcription Factor |
| Function | The SOX2 protein forms homodimers or heterodimers with other SOX proteins to bind specific DNA sequences (AACAAT/G) and regulate gene expression. |
| Primary Expression | Neural stem cells, neural progenitors, specific mature neurons |
| Molecular Weight | 34 kDa |
| Amino Acids | 80 aa |
| Pathways | Alzheimer's Disease Pathogenesis, Autophagy, Cell Cycle, Circadian Rhythm, Epigenetic |
| UniProt ID | P35745 |
| NCBI Gene ID | 6657 |
| Ensembl ID | ENSG00000104946 |
| OMIM | 184429 |
| GeneCards | SOX2 |
| Human Protein Atlas | SOX2 |
| Associated Diseases | aging, ALS, Alzheimer's Disease, disease, Inflammation |
| Interactions | ACTB, ACTG1, AGING, AKT, ALDH1L1, ALZHEIMER |
| KG Connections | 536 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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