| Gene Symbol | SMN |
| Aliases | SMNPROTEIN |
| Chromosome | 5q13.2. |
| Function | SMN is essential for cellular viability, and complete absence is embryonically lethal. |
| Primary Expression | Spinal Cord, Ca1, Cerebellum |
| Molecular Weight | 38 kDa |
| Amino Acids | 294 aa |
| Exons | 2 |
| Pathways | Tdp-43, Apoptosis, Er Stress, Cell Cycle, CRISPR-Cas |
| GeneCards | SMN |
| Human Protein Atlas | SMN |
| Tudor domain | Binds to symmetrically dimethylated arginine residues on Sm proteins |
| Proline-rich region | Mediates protein-protein interactions |
| YG box | Glycine-phenylalanine-rich region involved in self-oligomerization |
| snRNP assembly | SMN is essential for the assembly of the spliceosomal small nuclear ribonucleoproteins (snRNPs) U1, U2, U4, and U5 |
| Associated Diseases | Als, Amyotrophic Lateral Sclerosis, dementia, frontotemporal |
| Interactions | Actin, ALS, AMYOTROPHIC LATERAL SCLEROSIS, AND, CHMP7, MOTOR NEURONS |
| KG Connections | 115 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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