| Gene Symbol | SGK1 |
| Aliases | SGK1PROTEIN |
| Chromosome | 6q23 |
| Protein Type | Kinase |
| Function | SGK1 is a member of the AGC kinase family (PKA/PKB/PKC-related) with diverse cellular functions: [@firestone2003] |
| Subcellular Localization | </th><td>Cytoplasm, Nucleus</td></tr> |
| Molecular Weight | 49 kDa |
| Amino Acids | 433 aa |
| Exons | 13 |
| Pathways | mTOR, mtor |
| GeneCards | SGK1 |
| Human Protein Atlas | SGK1 |
| Akt-like hydrophobic motif (FXXFS/TY) | Regulatory site (Ser422) phosphorylated by mTORC2 |
| PDK1 phosphorylation site | Thr256 in the activation loop |
| N-terminal variable region | Contains nuclear localization signals |
| Associated Diseases | Als, Depression, Inflammation, Lymphoma, Ms |
| Interactions | AND, BDNF, CD4, CREB, CYTOKINES, DNA |
| KG Connections | 69 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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