| Gene Symbol | SDHA |
| Full Name | Succinate Dehydrogenase Complex Subunit A |
| Aliases | Page for SDHA Gene, Page for SDHA Protein |
| Chromosome | 5p15.33 |
| Protein Type | Enzyme |
| Function | SDHA is a catalytic subunit of succinate dehydrogenase (SDH), a heterotetrameric enzyme that functions in both the Krebs cycle (Complex II of the ETC). |
| Molecular Weight | 73 kDa |
| Pathways | Proteasome |
| UniProt ID | P31040 |
| NCBI Gene ID | 6389 |
| Ensembl ID | ENSG00000123594 |
| GeneCards | SDHA |
| Human Protein Atlas | SDHA |
| FAD-binding domain | Located at the N-terminus, binds flavin adenine dinucleotide (FAD) covalently |
| 2Fe-2S iron-sulfur cluster | Mediates electron transfer between succinate and ubiquinone |
| Associated Diseases | Parkinson |
| Interactions | aco2, ACO2, AGING, ATP, ATP5A1, BDNF |
| KG Connections | 167 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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