| Gene Symbol | RESTPROTEIN |
| Full Name | REST (RE1-Silencing Transcription Factor) / NRSF |
| Chromosome | 4q12 |
| Protein Family | Zinc finger transcription factor family |
| Function | is a zinc-finger transcriptional repressor that plays a fundamental role in establishing and maintaining neuronal identity. |
| Primary Expression | Neuron-specific, high in hippocampus and cortex |
| Molecular Weight | ~121 kDa (1,098 amino acids) |
| Amino Acids | 098 aa |
| UniProt ID | Q9Y2W1 |
| GeneCards | RESTPROTEIN |
| Human Protein Atlas | RESTPROTEIN |
| Associated Diseases | AD (cytoplasmic sequestration), Aging, Als, Alzheimer, Alzheimer's disease, Ataxia |
| Interactions | ALZHEIMER, ALZHEIMER'S DISEASE, AMPK, AND, APOER2, APOPTOSIS |
| SciDEX Hypotheses | REST Complex Dysregulation as Master Epigenetic Sw REST-like neuronal silencing programs suppress MAP |
| KG Connections | 348 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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