protein 2,057 words KG: RAC1PROTEIN
Contents

RAC1 Protein

🔬 Protein Info
Gene SymbolRAC1
AliasesRAC1PROTEIN
Functionis an important component in the neurobiology of neurodegenerative diseases.
Subcellular Localizationmultiple subcellular compartments including the cytoplasm, plasma membrane, dendritic spines, synapses, and mitochondria
Molecular Weight21.4 kDa
Amino Acids192 aa
PathwaysApoptosis, Autophagy, Dendritic Spine, Mtor, Nf-Κb
Ensembl IDENSG00000136238
GeneCardsRAC1
Human Protein AtlasRAC1
Associated DiseasesAls, Cancer, Diabetes, Encephalitis, Inflammation
InteractionsACTB, Actin, ACVR1, AKT, AKT1, ALZHEIMER
KG Connections483 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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UniProtWikipedia

Related Hypotheses (15)

Astroglial Gap Junction Coordination via Connexin-43 Phospho
Score: 0.72
CX43 hemichannel engineering enables size-selective mitochon
Score: 0.69
Astrocytic Connexin-43 Upregulation Enhances Neuroprotective
Score: 0.56
Microglial Efferocytosis Enhancement via GPR32 Superagonists
Score: 0.70
Purinergic P2Y12 Inverse Agonist Therapy
Score: 0.70
Microglial Purinergic Reprogramming
Score: 0.70
Reelin-Mediated Cytoskeletal Stabilization Protocol
Score: 0.69
Lysosomal Positioning Dynamics Modulation
Score: 0.69
Complement C1q Subtype Switching
Score: 0.66
Ephrin-B2/EphB4 Axis Manipulation
Score: 0.64
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Synaptic Phosphatidylserine Masking via Annexin A1 Mimetics
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
TREM2-mediated microglial tau clearance enhancement
Score: 0.62

Related Analyses (9)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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