protein 643 words KG: PGC1ALPHA
Contents

PGC-1α Protein

🔬 Protein Info
Gene SymbolPGC
Full Name1α Protein
AliasesPGC1ALPHA
FunctionPgc 1Α Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
GeneCardsPGC
Human Protein AtlasPGC
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (9)

Mitochondrial-Nuclear Epigenetic Cross-Talk Restoration
Score: 0.70
Arginine Methylation Enhancement Therapy
Score: 0.65
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.91
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.67

Related Analyses (8)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
GBA-Synuclein Loop Therapeutics for PD
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (13)

GWAS meta-analysis of major depressive disorder across three
exploratory · proposed · Score: 0.95
Differential GWAS of schizophrenia vs PTSD
exploratory · proposed · Score: 0.90
PGC-1α knockout effects on PV+ interneuron maturation
validation · proposed · Score: 0.90
PGC-1α knockout analysis of PV+ interneuron maturation
validation · proposed · Score: 0.85
TUG C-terminal product nuclear localization and PPARγ bindin
exploratory · proposed · Score: 0.85

See Also (8)

Neurofilament Medium Chain (NfM) - Biomarker
biomarker · KG edge: regulates
Parkinson Basal Ganglia Circuit
circuit · KG edge: regulates
HNRNPA1 Gene
gene · KG edge: regulates
lmx1b
gene · KG edge: regulates
NURR1 Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

LMX1B regulates PGC1ALPHA
PINK1 regulates PGC1ALPHA
SNCA regulates PGC1ALPHA
SFPQ regulates PGC1ALPHA
NFM regulates PGC1ALPHA
HNRNPA1 regulates PGC1ALPHA
PGC1ALPHA regulates NURR1
PGC1ALPHA regulates PARK7
PARK7 regulates PGC1ALPHA
PGC1ALPHA regulates LMX1B

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