Contents

PER1 Protein

🔬 Protein Info

Gene Symbol	Period Circadian Regulator 1
Chromosome	17p13.1
Function	PER1 (Period Circadian Regulator 1) is a core component of the mammalian circadian clock.
Subcellular Localization	</strong></td><td>Nucleus (primary), Cytoplasm</td></tr>
Molecular Weight	136 kDa
Pathways	Amyloid, Mtor, Pi3K/Akt, circadian regulation
UniProt ID	O15055
NCBI Gene ID	5441
Ensembl ID	ENSG00000132359
OMIM	602260
bHLH Domain	Protein-protein interactions
PAS-A Domain	Dimerization with PER2
PAS-C Domain	CRY protein interaction
CKBD	Cryptochrome binding domain
Nuclear Localization Signal	NLS for nuclear import
Associated Diseases	ALS, autism spectrum disorder
Known Drugs/Compounds	lithium
Interactions	AKT, AND, APP, BMAL1, CLOCK, CRY1
KG Connections	148 knowledge graph edges
Databases	GeneCards HPA STRING

No AI portrait yet

Knowledge Graph