| Gene Symbol | PDGFR |
| Full Name | Beta Protein |
| Aliases | PDGFRBPROTEIN |
| Function | PDGFR-beta (PDGFRB) is a receptor tyrosine kinase that translates platelet-derived growth-factor ligands into pericyte survival, vascular maturation, and neurovascular homeostasis programs. |
| Pathways | MAPK signaling, PI3K-AKT-mTOR signaling, glymphatic clearance, blood-brain barrier |
| UniProt ID | P09619 |
| GeneCards | PDGFR |
| Human Protein Atlas | PDGFR |
| Protein Name | Platelet-Derived Growth Factor Receptor Beta (PDGFR-Beta) |
| Gene | PDGFRB |
| Receptor Class | Receptor tyrosine kinase (RTK) |
| Primary Ligands | PDGF-B Protein, PDGF-AB, PDGF-DD |
| Functional Axis | Pericyte maintenance, BBB integrity, neurovascular signaling |
| Associated Diseases | glioblastoma, Huntington's disease |
| Interactions | ERK, GBM, IL2, MAPK, PI3K |
| KG Connections | 32 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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