| Gene Symbol | PDE4D |
| Full Name | Phosphodiesterase 4D (cAMP-specific) |
| Aliases | Phosphodiesterase 4D |
| Chromosome | 5q12.1 |
| Function | is a member of the phosphodiesterase 4 (PDE4) family that specifically hydrolyzes cyclic adenosine monophosphate (cAMP), serving as a key regulator of cAMP signaling in cells. |
| Primary Expression | Brain (cortex, hippocampus, cerebellum), immune cells, smooth muscle |
| Subcellular Localization | </strong></td><td>Cytoplasm</td></tr> |
| Amino Acids | 886 aa |
| Pathways | Camp Signaling |
| UniProt ID | [Q08499](https://www.uniprot.org/uniprot/Q08499) |
| Ensembl ID | ENSG00000100162 |
| GeneCards | PDE4D |
| Human Protein Atlas | PDE4D |
| Associated Diseases | neurodegeneration |
| Interactions | CREB, CREB1, GENES, MITOCHONDRIAL DYSFUNCTION, MITOPHAGY, OXIDATIVE STRESS |
| KG Connections | 55 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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