| Gene Symbol | DJ |
| Full Name | 1 (PARK7) Protein |
| Aliases | PARK7PROTEIN |
| Function | Dj 1 Protein (Park7) is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes. |
| Subcellular Localization | </b></td><td>Cytoplasm, Nucleus, Mitochondria</td></tr> |
| GeneCards | DJ |
| Human Protein Atlas | DJ |
| α/β Sandwich | 8 β-strands surrounded by 6 α-helices |
| Catalytic Cysteine | Cysteine 106 (C106) — critical for enzymatic activity |
| RNA-Binding Domain | C-terminal region involved in RNA binding |
| Dimerization Interface | Forms functional homodimers |
| Oxidation | C106 oxidized to sulfinic/sulfonic acid |
| Phosphorylation | Multiple phosphorylation sites (S66, Y127) |
| Sumoylation | SUMO conjugation at K6 |
| Deglutathionylase | Removes GSH adducts from proteins |
| Associated Diseases | AD, Als, Alzheimer, Alzheimer's disease, Amyotrophic Lateral Sclerosis |
| Interactions | ACETYL-COA, AD, AGING, AKT, Alpha-Synuclein, ALS |
| KG Connections | 610 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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