| Gene Symbol | PAK1 |
| Full Name | P21 (RAC1) Activated Kinase 1 |
| Aliases | PAK1PROTEIN |
| Chromosome | 11q13.5 |
| Protein Type | Serine/Threonine Kinase |
| Function | encodes a serine/threonine kinase that serves as a critical downstream effector of the Rho GTPases Rac1 and Cdc42. |
| Primary Expression | the brain, particularly in the hippocampus and cerebral cortex, where it plays essential roles in dendritic spine morphogenesis, synapse formation, an |
| Subcellular Localization | </strong></td><td>Cytoplasm, Membrane, Nucleus</td></tr> |
| Molecular Weight | 65 kDa |
| Amino Acids | 545 aa |
| Exons | 15 |
| Pathways | Apoptosis, Autophagy, Camp Signaling, Circadian Rhythm, Invasion |
| UniProt ID | [Q13153](https://www.uniprot.org/uniprot/Q13153) |
| Ensembl ID | ENSG00000149269 |
| OMIM | 602590 |
| GeneCards | PAK1 |
| Human Protein Atlas | PAK1 |
| Associated Diseases | Als, Cancer, Encephalitis, Inflammation, Multiple Sclerosis |
| Interactions | AND, APOPTOSIS, ATG12, ATG16L1, ATG5, AUTOPHAGY |
| KG Connections | 143 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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